Facilities and Services
Genomics
State-of-the-art Sequencing Technology Enabling Discoveries
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DAVID FANG Genomics Core Specialist |
The ability to sequence DNA and to detect the expression of tens of thousands of genes in parallel has become a mainstay of 21st century biology. Within the Genomics Suite, DNA sequencing supports research across the campus and extends to projects in collaboration with other institutions, including the sequencing of disease-causing organisms. Robotics technologies extend this efficiency and assist in many applications, such as the mapping of genomes. Such knowledge permits scientists to translate basic research into answers to important challenges facing society such as food, diseases and sustainable resources. Within the Gene Expression suite, custom and commercial gene arrays permit the monitoring of thousands of genes within an organism. Understanding changes that cells undergo during growth or as a result of pathogens often demands highly specialized instrumentation, such as automated cell sorters. The Institute maintains such equipment as well as expertise in their operation and assistance in experimental design. All aspects of the Genomics and Gene Expression Suites are supported by in-depth hands-on training with our specialists who encourage collaborative research within UC Riverside and with external researchers interested in drawing on our expertise for their own research.
A powerful new research approach embraced at IIGB is chemical genomics. This is an emerging field at the intersection of chemistry and biology that focuses on the screening of thousands of drug-like chemicals on living organisms using robotic instrumentation for highly automated handling of chemicals and biological samples. Currently, IIGB houses chemical libraries as well as fluid robotics (Microscopy and Genomics Cores), chemical database tools (Bioinformatics Core) and expertise in biological screening of chemicals.
The Genomics Core is staffed by David Fang (Specialist), Barbara Walter (Staff Research Associate) and Clay Clark (Laboratory Assistant).
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