UCR

Institute for Integrative Genome Biology



Members


Rong HaiRong Hai

Assistant Professor

Mailing Address:

Plant Pathology and Microbiology
Boyce Hall / 4488
University of California
Riverside, CA 92521

Phone: (951) 827-3910
Fax: (951) 827-4294
Email: ronghai@ucr.edu

Degree(s):

PhD  2006  University of California, Berkeley
BS/MS  2000  Jinan University

College/Division Affiliation:

College of Natural and Agricultural Sciences

Center/Inst Affiliation(s):

Center for Conservation Biology

Areas Of Expertise:

Viral Molecular Pathology, Virus Host Interactions and Vaccine Development

Awards / Honors:

2013-14  NIH Training Program in Mechanisms of Virus-Host Interactions
2004-06  The University-wide AIDS Research Program(UARP), UC Dissertation Fellowship 

Research Summary:

Our laboratory has broadly interests on the molecular characterization of emerging negative strand RNA viruses with focuses on discovering novel viral virulence signatures and molecular viral-host interactions. Currently, we use influenza viruses as the primary model system.

Influenza virus, family Orthomyxoviridae, is a negative-strand RNA virus with 8 segments and is grouped by its antigenic properties as type A, B or C. Influenza virus is a major human respiratory pathogen. However, only types A and B, are responsible for seasonal epidemics resulting in approximately 35,000 (US) and 500,000 (worldwide) deaths annually, while type C causes mild respiratory illness.  In addition, influenza A virus can cause pandemics, which occurs every 10-50 years. Due to the lack of pre-existing immunity in humans, pandemic cases usually increase mortality and severity of the infection. For example, during 1918-1919 influenza pandemic, about one third of the world's population (or ≈500 million persons) were infected and had clinically apparent illnesses.

We combine molecular, biochemical, and imaging techniques to understand how viruses replicate and to explore virus-host interactions. We also have interests, driven by our research goals, in developing methods for manipulating genomes of other emerging viruses.

Selected Publications:

List of publications from PubMed

 


More Information

General Campus Information

University of California, Riverside
900 University Ave.
Riverside, CA 92521
Tel: (951) 827-1012

Career OpportunitiesUCR Libraries
Campus StatusDirections to UCR

Genomics Information

Institute of Integrative Genome Biology
2150 Batchelor Hall

Tel: (951) 827-7177
E-mail: Aurelia Espinoza, Managing Director

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