Institute for Integrative Genome Biology


David LoDavid Lo

Distinguished Professor of Biomedical Sciences

Mailing Address:

Biomedical Sciences
Webber /2146
University of California
Riverside, CA 92521

Phone: (951) 827-4553
Fax: (951) 827-5504
Email: david.lo@ucr.edu 

UCR Living the Promise Profile (2012)


PhD 1986 University of Pennsylvania
MD 1986 University of Pennsylvania
BA 1980 Haverford College

College/Division Affiliation:

Division of Biomedical Sciences

Center/Inst Affiliation(s):

Center for Disease Vector Research

Areas Of Expertise:

Mucosal Immunology; Allergy; Vaccines

Awards / Honors:

2005  Fellow of the American Association for the Advancement of Science
1999  Chevron Conservation Award
1979  Mycological Society of American Graduate Fellowship
1974  Who's Who in American College and Universities

Research Summary:

Research in my laboratory is concerned with the study of the basic developmental biology of mucosal immune tissue, CD4 T cell homeostatic regulation, and the role of relB in the regulation of NF-kappaB activity and cellular differentiation. One of our major projects is on the development and function of M cells, which are a specialized subset of epithelial cells associated with mucosal immune tissues. These cells are responsible for the surveillance of the airway and intestine, by performing a selective sampling of particles from the lumen. We are working to use this system to develop a needle-free vaccine delivery technology that may be conveniently and cheaply applied to vaccination against infectious agents such as influenza. A second major project is focused on the role of the chemokine receptor CCR7 in the regulation of CD4 T cell survival and differentiation. Our studies have suggested that CCR7 ligands regulate not only lymphocyte migration, but also their survival and development into effector cells.

Related Press Releases:

Selected Publications:

List of publications from PubMed


More Information

General Campus Information

University of California, Riverside
900 University Ave.
Riverside, CA 92521
Tel: (951) 827-1012

Career OpportunitiesUCR Libraries
Campus StatusDirections to UCR

Genomics Information

Institute of Integrative Genome Biology
2150 Batchelor Hall

Tel: (951) 827-7177
E-mail: Aurelia Espinoza, Managing Director